Prostacyclin inhibits pancreatic secretion.

@article{Konturek1980ProstacyclinIP,
  title={Prostacyclin inhibits pancreatic secretion.},
  author={Stanisław Jan Konturek and Janina Tasler and Jolanta Jaworek and Marek Cieszkowski and Wiesław W. Pawlik},
  journal={The American journal of physiology},
  year={1980},
  volume={238 6},
  pages={
          G531-6
        }
}
Prostacyclin (PGI2), the major product of arachidonate metabolism in the gastrointestinal tract, was shown to affect gastric blood flow and gastric secretion, but it is unknown whether it also affects pancreatic secretion. This study was designed to determine the influence of PGI2 on pancreatic secretion under basal conditions and in response to exogenous and endogenous stimulants. PGI2 alone given in graded intravenous doses caused a slight pancreatic bicarbonate and protein secretion in… 
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