Prostacyclin and prostaglandin E2 effects on adrenergic transmission in the kidney of anesthetized dog.

  • H Susić, K Malik
  • Published 1981 in
    The Journal of pharmacology and experimental…


The effect of prostaglandin E2 (PGE2) and prostacyclin (PGI2) on the renal venous output of the adrenergic transmitter and on the renal vasoconstriction produced by sympathetic nerve stimulation and by norepinephrine was studied in pentobarbital-anesthetized dog. Renal arterial infusion of either PGE2 or PGI2 (4 ng kg-1 min-1) increased blood flow to the… (More)


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