Prostacyclin: effects on cyclic AMP in bone cells.

@article{Robin1982ProstacyclinEO,
  title={Prostacyclin: effects on cyclic AMP in bone cells.},
  author={J. C. Robin and M J Brown and N. Weinfeld and R. Dziak},
  journal={Research communications in chemical pathology and pharmacology},
  year={1982},
  volume={35 1},
  pages={
          43-9
        }
}
  • J. Robin, M. Brown, R. Dziak
  • Published 1 July 1982
  • Biology, Medicine
  • Research communications in chemical pathology and pharmacology

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Prostacyclin Suppresses Twist Expression in the Presence of Indomethacin in Bone Marrow-Derived Mesenchymal Stromal Cells

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    Medical science monitor : international medical journal of experimental and clinical research
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APD shows an outstanding effect on the bone loss at the very place where it occurs preferentially in the paraplegics (the trabecular metaphysis), but this and other effects affect the controls as well.

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TLDR
The literature suggests that Iloprost administration can be a viable option in the management of bone marrow oedema and early stages of osteonecrosis, and its effect on bone homeostasis needs further elucidation.