Prospects for treatment of paraquat-induced lung fibrosis with immunosuppressive drugs and the need for better prediction of outcome: a systematic review.

@article{Eddleston2003ProspectsFT,
  title={Prospects for treatment of paraquat-induced lung fibrosis with immunosuppressive drugs and the need for better prediction of outcome: a systematic review.},
  author={Michael Eddleston and Martin F. Wilks and Nicholas Alan Buckley},
  journal={QJM : monthly journal of the Association of Physicians},
  year={2003},
  volume={96 11},
  pages={809-24}
}
BACKGROUND Acute paraquat self-poisoning is a significant problem in parts of Asia, the Pacific and the Caribbean. Ingestion of large amounts of paraquat results in rapid death, but smaller doses often cause a delayed lung fibrosis that is usually fatal. Anti-neutrophil ('immunosuppressive') treatment has been recommended to prevent lung fibrosis, but there is no consensus on efficacy. AIM To review the evidence for the use of immunosuppression in paraquat poisoning, and to identify validated… CONTINUE READING
39 Citations
59 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 59 references

Paraquat. In: Handbook of pesticide toxicology, 2 edn

  • EA Lock, MF Wilks
  • 2001
Highly Influential
6 Excerpts

Treatment of moderate to severe paraquat poisoning with dexamethasone/cyclophosphamide combination: a case series from the toxicology consultation service at Siriraj Hospital, Bangkok, Thailand

  • S Chomchai, C. Chomchai
  • J Toxicol Clin Toxicol
  • 2003
2 Excerpts

Similar Papers

Loading similar papers…