Prospects for the use of NK cells in immunotherapy of human cancer

@article{Ljunggren2007ProspectsFT,
  title={Prospects for the use of NK cells in immunotherapy of human cancer},
  author={H O Ljunggren and Karl-Johan Malmberg},
  journal={Nature Reviews Immunology},
  year={2007},
  volume={7},
  pages={329-339}
}
Current insights into the molecular specificities that regulate natural killer (NK)-cell function suggest that it might be possible to design NK-cell-based immunotherapeutic strategies against human cancer. Here, we describe evidence for NK-cell targeting of human tumours and address crucial questions that, in our opinion, require consideration for the development of successful NK-cell-based therapies. Appropriately used, we predict that NK cells will have a role, both directly and in… CONTINUE READING
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