Prospects for new restorative and neuroprotective treatments in Parkinson's disease

  title={Prospects for new restorative and neuroprotective treatments in Parkinson's disease},
  author={Stephen B. Dunnett and Anders Bj{\"o}rklund},
The degeneration of forebrain dopamine systems in Parkinson's disease has been an effective target for pharmaceutical research over the past four decades. However, although dopamine replacement may alleviate the symptoms of the disease, it does not halt the underlying neuronal degeneration. The past decade has seen major advances in identifying discrete genetic and molecular causes of parkinsonism and mapping the events involved in nigral cell death. This new understanding of the pathogenesis… CONTINUE READING
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