Prospects for Improving Brain Function in Individuals with Down Syndrome

@article{Costa2013ProspectsFI,
  title={Prospects for Improving Brain Function in Individuals with Down Syndrome},
  author={A. Costa and J. J. Scott-McKean},
  journal={CNS Drugs},
  year={2013},
  volume={27},
  pages={679-702}
}
  • A. Costa, J. J. Scott-McKean
  • Published 2013
  • Psychology, Medicine
  • CNS Drugs
    • Down syndrome (DS), which results from an extra copy of chromosome 21 (trisomy 21), is the most common genetically defined cause of intellectual disability. Although no pharmacotherapy aimed at counteracting the cognitive and adaptive deficits associated with this genetic disorder has been approved at present, there have been several new promising studies on pharmacological agents capable of rescuing learning/memory deficits seen in mouse models of DS. Here, we will review the available mouse… CONTINUE READING
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    ncbi.nlm.nih.gov
    54 Citations
    Highly Influencial Citations
    1
    Background Citations
    18
    Methods Citations
    3

    Paper Mentions

    Interventional Clinical Trial
    Down Syndrome Memantine Follow-up Study
    The purpose of this research study is to learn if the medication Memantine Hydrochloride (the study medication) can help adolescents and young adults with Down syndrome. Dr. Alberto… Expand
    ConditionsDown Syndrome, Intellectual Disability
    InterventionDrug
    University Hospitals Cleveland Medical Center
    October 2014 - December 2019
    54 Citations
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