Prospects for Improving Brain Function in Individuals with Down Syndrome

  title={Prospects for Improving Brain Function in Individuals with Down Syndrome},
  author={A. Costa and J. J. Scott-McKean},
  journal={CNS Drugs},
  • A. Costa, J. J. Scott-McKean
  • Published 2013
  • Psychology, Medicine
  • CNS Drugs
  • Down syndrome (DS), which results from an extra copy of chromosome 21 (trisomy 21), is the most common genetically defined cause of intellectual disability. Although no pharmacotherapy aimed at counteracting the cognitive and adaptive deficits associated with this genetic disorder has been approved at present, there have been several new promising studies on pharmacological agents capable of rescuing learning/memory deficits seen in mouse models of DS. Here, we will review the available mouse… CONTINUE READING
    54 Citations

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