Prospective validation of a novel renal activity index of lupus nephritis.

  title={Prospective validation of a novel renal activity index of lupus nephritis.},
  author={Gaurav Gulati and Michael R Bennett and Khalid M. Abulaban and Huijuan Song and Xiaolan Zhang and Qing Ma and S V Brodsky and Tibor Nadasdy and Christopher Haffner and Kasha Wiley and Stacy Payne Ardoin and Prasad Devarajan and Jun Ying and Brad H. Rovin and Hermine I Brunner},
  volume={26 9},
Objectives The renal activity index for lupus (RAIL) score was developed in children with lupus nephritis as a weighted sum of six urine biomarkers (UBMs) (neutrophil gelatinase-associated lipocalin, monocyte chemotactic protein 1, ceruloplasmin, adiponectin, hemopexin and kidney injury molecule 1) measured in a random urine sample. We aimed at prospectively validating the RAIL in adults with lupus nephritis. Methods Urine from 79 adults was collected at the time of kidney biopsy to assay the… CONTINUE READING