Prospective study of serum selenium levels and incident esophageal and gastric cancers.

  title={Prospective study of serum selenium levels and incident esophageal and gastric cancers.},
  author={Steven D. Mark and You Lin Qiao and Sanford M. Dawsey and Yelena P Wu and Hormuzd A. Katki and Elaine W. Gunter and Joseph F. Jr. Fraumeni and William J. Blot and Zhi Wei Dong and Philip R. Taylor},
  journal={Journal of the National Cancer Institute},
  volume={92 21},
BACKGROUND From March 1986 through May 1991, we conducted a randomized nutritional intervention trial, the General Population Trial, in Linxian, China, a region with epidemic rates of squamous esophageal and adenomatous gastric cardia cancers. We found that participants who received selenium, beta-carotene, and vitamin E had significantly lower cancer mortality rates than those who did not. In the current study, we examined the relationship between selenium levels measured in pretrial (1985… CONTINUE READING
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