Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing

@article{Forsyth1997ProspectiveSO,
  title={Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing},
  author={Peter A. Forsyth and Casilda Balmaceda and Kendra Peterson and Andrew David Seidman and Penny Brasher and Lisa M DeAngelis},
  journal={Journal of Neuro-Oncology},
  year={1997},
  volume={35},
  pages={47-53}
}
Background. Paclitaxel-induced peripheral neuropathy (PN) may be severeand dose-limiting at initial doses ≥ 275 mg/M2, but itsneurotoxicity at doses ≤ 250 mg/M2 has been incompletelycharacterized. The purposes of this study were to characterize and quantifypaclitaxel-induced PN and to determine the utility of quantitative sensorytesting (QST). Methods. We prospectively examined clinically and by QST 37women with metastatic breast cancer, treated with paclitaxel (200–250mg/m2) (average number of… CONTINUE READING

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