Prospective study of asymptomatic valvular aortic stenosis. Clinical, echocardiographic, and exercise predictors of outcome.

@article{Otto1997ProspectiveSO,
  title={Prospective study of asymptomatic valvular aortic stenosis. Clinical, echocardiographic, and exercise predictors of outcome.},
  author={Catherine M. Otto and Ian G. Burwash and Malcolm E Legget and Brad I Munt and Manabu Fujioka and Nancy L. Healy and Carol D. Kraft and Carolyn Y. Miyake-Hull and Rebecca Gibbons Schwaegler},
  journal={Circulation},
  year={1997},
  volume={95 9},
  pages={
          2262-70
        }
}
BACKGROUND Only limited data on the rate of hemodynamic progression and predictors of outcome in asymptomatic patients with valvular aortic stenosis (AS) are available. METHODS AND RESULTS In 123 adults (mean age, 63 +/- 16 years) with asymptomatic AS, annual clinical, echocardiographic, and exercise data were obtained prospectively (mean follow-up of 2.5 +/- 1.4 years). Aortic jet velocity increased by 0.32 +/- 0.34 m/s per year and mean gradient by 7 +/- 7 mm Hg per year; valve area… CONTINUE READING

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