Prospective randomized trial of lisuride infusion versus oral levodopa in patients with Parkinson's disease.

@article{Stocchi2002ProspectiveRT,
  title={Prospective randomized trial of lisuride infusion versus oral levodopa in patients with Parkinson's disease.},
  author={F. Stocchi and S. Ruggieri and L. Vacca and C. Olanow},
  journal={Brain : a journal of neurology},
  year={2002},
  volume={125 Pt 9},
  pages={
          2058-66
        }
}
Motor complications are a major source of disability for patients with advanced Parkinson's disease. Surgical therapies provide benefit to some, but these treatments are expensive and associated with adverse effects. Current research indicates that motor complications are associated with abnormal, intermittent, pulsatile stimulation of denervated dopamine receptors using short acting dopaminergic agents such as levodopa. Retrospective studies suggest that the use of longer-acting more… Expand
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