Prospective randomized trial comparing shock wave lithotripsy and ureteroscopy for lower pole caliceal calculi 1 cm or less.


PURPOSE The optimal management of lower pole renal calculi is controversial. We compared shock wave lithotripsy (SWL) and ureteroscopy (URS) for the treatment of patients with small lower pole stones in a prospective, randomized, multicenter trial. MATERIALS AND METHODS A total of 78 patients with 1 cm or less isolated lower pole stones were randomized to SWL or URS. The primary outcome measure was stone-free rate on noncontrast computerized tomography at 3 months. Secondary outcome parameters were length of stay, complication rates, need for secondary procedures and patient derived quality of life measures. RESULTS A total of 67 patients randomized to SWL (32) or URS (35) completed treatment. The 2 groups were comparable with respect to age, sex, body mass index, side treated and stone surface area. Operative time was significantly shorter for SWL than URS (66 vs 90 minutes). At 3 months of followup 26 and 32 patients who underwent SWL and URS had radiographic followup that demonstrated a stone-free rate of 35% and 50%, respectively (p not significant). Intraoperative complications occurred in 1 SWL case (unable to target stone) and in 7 URS cases (failed access in 5 and perforation in 2), while postoperative complications occurred in 7 SWL and 7 URS cases. Patient derived quality of life measures favored SWL. CONCLUSIONS This study failed to demonstrate a statistically significant difference in stone-free rates between SWL and URS for the treatment of small lower pole renal calculi. However, SWL was associated with greater patient acceptance and shorter convalescence.

DOI: 10.1016/j.juro.2008.03.140
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@article{Pearle2005ProspectiveRT, title={Prospective randomized trial comparing shock wave lithotripsy and ureteroscopy for lower pole caliceal calculi 1 cm or less.}, author={Margaret Sue Pearle and James E. Lingeman and Raymond John Leveillee and Ramsay L. Kuo and Glenn M. Preminger and Robert B. Nadler and Joseph N Macaluso and Manoj Monga and Udaya Kumar and John Dushinski and David Mois Albala and James Stuart Wolf and Dean G. Assimos and Michael D. Fabrizio and Larry C. Munch and Stephen Y. Nakada and Brian K. Auge and John R D'A Honey and Kenneth E Ogan and John G. Pattaras and Elspeth Marguerita McDougall and Timothy D. Averch and Thomas M. T. Turk and Paul K Pietrow and Stephanie L Watkins}, journal={The Journal of urology}, year={2005}, volume={173 6}, pages={2005-9} }