Prospective randomised controlled trial comparing trigone-sparing versus trigone-including intradetrusor injection of abobotulinumtoxinA for refractory idiopathic detrusor overactivity.

@article{Manecksha2012ProspectiveRC,
  title={Prospective randomised controlled trial comparing trigone-sparing versus trigone-including intradetrusor injection of abobotulinumtoxinA for refractory idiopathic detrusor overactivity.},
  author={Rustom Pervez Manecksha and Ivor Michael Cullen and Sarfraz Ahmad and G P Mcneill and Robert Joseph Flynn and Thomas E. McDermott and Ronald G. Grainger and John Thornhill},
  journal={European urology},
  year={2012},
  volume={61 5},
  pages={928-35}
}
BACKGROUND Botulinum toxin A is effective for treatment of idiopathic detrusor overactivity (IDO). The trigone is generally spared because of the theoretical risk of vesicoureteric reflux (VUR), although studies assessing injection sites are lacking. OBJECTIVE Evaluate efficacy and safety of trigone-including versus trigone-sparing intradetrusor injections of abobotulinumtoxinA in patients with IDO. DESIGN, SETTING, AND PARTICIPANTS Twenty-two patients from one centre were randomised to… CONTINUE READING

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