Prospective placebo-controlled randomized trial of lexipafant in predicted severe acute pancreatitis.

@article{Mckay1997ProspectivePR,
  title={Prospective placebo-controlled randomized trial of lexipafant in predicted severe acute pancreatitis.},
  author={C. J. Mckay and F J Curran and Christine Sharples and John N Baxter and Clement W. Imrie},
  journal={The British journal of surgery},
  year={1997},
  volume={84 9},
  pages={1239-43}
}
BACKGROUND Many patients with severe acute pancreatitis develop organ system failure during the first few days of illness, and this accounts for the majority of early deaths. No specific therapy is available and treatment remains supportive. METHODS In a randomized controlled trial conducted in 11 hospitals in the West of Scotland, 50 patients with predicted severe acute pancreatitis were selected from 188 screened over a 14-month period. Patients received placebo or lexipafant, a potent… CONTINUE READING

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