Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody.

@article{Battula2008ProspectiveIA,
  title={Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody.},
  author={Venkata Lokesh Battula and Sabrina Treml and Harald Abele and H H B{\"u}hring},
  journal={Differentiation; research in biological diversity},
  year={2008},
  volume={76 4},
  pages={326-36}
}
We have recently shown that frizzled-9 (FZD9, CD349) is expressed on the cell surface of cultured mesenchymal stromal cells (MSC) derived from the human bone marrow (BM) and chorionic placenta (PL). To study whether FZD9 is also a marker for naive mesenchymal stem cells (MSC), we analyzed the expression pattern of FZD9 on freshly isolated PL cells and determined the clonogenic potential of isolated FZD9(+) cells using the colony-forming units-fibroblastic (CFU-F) assay. About 0.2% of isolated… CONTINUE READING

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