Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry.

@article{Wax2005ProspectiveGO,
  title={Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry.},
  author={Adam P Wax and John W. Pyhtila and Robert Nicholas Graf and Ronald G. Nines and Charles W. Boone and Ramachandra R. Dasari and M. S. Feld and Vernon E. Steele and Gary David Stoner},
  journal={Journal of biomedical optics},
  year={2005},
  volume={10 5},
  pages={
          051604
        }
}
Angle-resolved low-coherence interferometry (a/LCI) is used to obtain quantitative, depth-resolved nuclear morphology measurements. We compare the average diameter and texture of cell nuclei in rat esophagus epithelial tissue to grading criteria established in a previous a/LCI study to prospectively grade neoplastic progression. We exploit the depth resolution of a/LCI to exclusively examine the basal layer of the epithelium, approximately 50 to 100 microm beneath the tissue surface, without… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 27 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 14 REFERENCES

Similar Papers

Loading similar papers…