Prospective evaluation of quality of life and neurocognitive effects in patients with multiple brain metastases receiving whole-brain radiotherapy with or without thalidomide on Radiation Therapy Oncology Group (RTOG) trial 0118.

@article{Corn2008ProspectiveEO,
  title={Prospective evaluation of quality of life and neurocognitive effects in patients with multiple brain metastases receiving whole-brain radiotherapy with or without thalidomide on Radiation Therapy Oncology Group (RTOG) trial 0118.},
  author={Benjamin Corn and Jennifer Moughan and Jonathan P. S. Knisely and Sherry W Fox and Arnab Chakravarti and W. K. Alfred Yung and Walter J. Curran and Hillary Robins and David G. Brachman and Randal H. Henderson and Minesh P. Mehta and Benjamin Movsas},
  journal={International journal of radiation oncology, biology, physics},
  year={2008},
  volume={71 1},
  pages={71-8}
}
PURPOSE Radiation Therapy Oncology Group (RTOG) 0118 randomized patients with multiple brain metastases to whole-brain radiotherapy (WBRT) +/- thalidomide. This secondary analysis of 156 patients examined neurocognitive and quality of life (QOL) outcomes. METHODS AND MATERIALS Quality of life was determined with the Spitzer Quality of Life Index (SQLI). The Folstein Mini-Mental Status Exam (MMSE) assessed neurocognitive function. SQLI and MMSE were administered at baseline and at 2-month… CONTINUE READING

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