Prospective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabine.

@article{Numico2005ProspectiveEO,
  title={Prospective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabine.},
  author={Gianmauro Numico and Ornella Garrone and Vincenzo Dongiovanni and Nicola Silvestris and Ida Colantonio and Gianna Di Costanzo and Cristina Granetto and Marcella Occelli and Elena Fea and Abdelamid Heouaine and Milena Gasco and Marco Carlo Merlano},
  journal={Cancer},
  year={2005},
  volume={103 5},
  pages={994-9}
}
BACKGROUND Cancer and cisplatin-based chemotherapy both are well recognized risk factors for coagulation disorders and thrombosis. However, vascular events (VEs) seldom are considered adverse effects of treatment and may not even be taken into account in reports of chemotherapy trials. METHODS VEs were recorded prospectively in a population of patients with nonsmall-cell lung carcinoma (NSCLC) who were treated consecutively with cisplatin and gemcitabine using a diagnostic flow chart based on… CONTINUE READING
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