Prospective comparison of the diagnostic potential of real-time PCR, double-sandwich enzyme-linked immunosorbent assay for galactomannan, and a (1-->3)-beta-D-glucan test in weekly screening for invasive aspergillosis in patients with hematological disorders.

@article{Kawazu2004ProspectiveCO,
  title={Prospective comparison of the diagnostic potential of real-time PCR, double-sandwich enzyme-linked immunosorbent assay for galactomannan, and a (1-->3)-beta-D-glucan test in weekly screening for invasive aspergillosis in patients with hematological disorders.},
  author={Masahito Kawazu and Yoshinobu Kanda and Yasuhito Nannya and Katsunori Aoki and Mineo Kurokawa and Shigeru Chiba and Toru Motokura and Hisamaru Hirai and Seishi Ogawa},
  journal={Journal of clinical microbiology},
  year={2004},
  volume={42 6},
  pages={
          2733-41
        }
}
The establishment of an optimal noninvasive method for diagnosing invasive aspergillosis (IA) is needed to improve the management of this life-threatening infection in patients with hematological disorders, and a number of noninvasive tests for IA that target different fungal components, including galactomannan, (1-->3)-beta-d-glucan (BDG), and Aspergillus DNA, have been developed. In this study, we prospectively evaluated the diagnostic potential of three noninvasive tests for IA that were… CONTINUE READING

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