Prospective cohort study of the feasibility and yield of household child tuberculosis contact screening in Uganda.

@article{Bonnet2017ProspectiveCS,
  title={Prospective cohort study of the feasibility and yield of household child tuberculosis contact screening in Uganda.},
  author={Maryline Bonnet and Catherine Kyakwera and Naomi Kyomugasho and Daniel Atwine and Frank R Mugabe and Margaret Nansumba and Yap Boum Ii and Juliet Mwanga-Amumpaire and Julius P. Kiwanuka},
  journal={The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease},
  year={2017},
  volume={21 8},
  pages={
          862-868
        }
}
  • M. Bonnet, C. Kyakwera, +6 authors J. Kiwanuka
  • Published 1 August 2017
  • Medicine
  • The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
SETTING Screening and isoniazid preventive therapy (IPT) of child contacts of tuberculosis (TB) patients is poorly implemented in resource-limited countries, in part due to difficulties in TB diagnosis in children. OBJECTIVE To assess the feasibility and yield of hospital-based screening and IPT in Uganda, and to evaluate the utility of symptom-based screening. DESIGN Household child (age <5 years) contacts of adults with pulmonary TB were assessed for TB or latent tuberculous infection… 
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Effectiveness of WHO's pragmatic screening algorithm for child contacts of tuberculosis cases in resource-constrained settings: a prospective cohort study in Uganda.
Yield of systematic household contact investigation for tuberculosis in a high-burden metropolitan district of South Africa
TLDR
The high yield of new TB observed in this pilot study demonstrates that targeted SHCI among household contacts of all four the WHO-recommended categories of infectious TB index cases – and male and coughing contacts, in particular – should be maximised.
Screening tests for active pulmonary tuberculosis in children
TLDR
To estimate the sensitivity and specificity of the presence of one or more tuberculosis symptoms, or symptom combinations; chest radiography (CXR); Xpert MTB/RIF; Xpert Ultra; and combinations of these as screening tests for detecting active pulmonary childhood tuberculosis in the following groups, six databases were searched.
Improving TPT Uptake: A Cluster-Randomized Trial of Symptom-Based Versus Tuberculin Skin Test-Based Screening of Household Tuberculosis Contacts Less than 5 Years of Age.
TLDR
Symptom-based screening did not improve the proportion of identified child contacts evaluated or initiated on TPT compared to TST-based Screening, and further research is needed to identify bottlenecks and evaluate interventions to ensure all child contacts receive TPT.
Diagnosis of childhood tuberculosis in Pakistan: are national guidelines used by private health care providers?
Contact Screening and Isoniazid Preventive Therapy Initiation for Under-Five Children among Pulmonary Tuberculosis-Positive Patients in Bahir Dar Special Zone, Northwest Ethiopia: A Cross-Sectional Study
TLDR
Contact screening practice and isoniazid preventive therapy initiation of children under the age of 5 in Bahir Dar zone were very low, and intimate family contact with pulmonary tuberculosis-positive patients, place of service delivery, and attitude towards screening are the key factors of contact screening.
How do private practitioners in Pakistan manage children suspected having tuberculosis? A cross sectional study
TLDR
This study showed that many private providers referred children suspected having TB to laboratories for further diagnosis, but the cases identified in these investigations were often not notified to the NTP.
A scoping review of paediatric latent tuberculosis infection care cascades: initial steps are lacking
Background and objectives Identifying and treating children with latent tuberculosis infection (TB infection) is critical to prevent progression to TB disease and to eliminate TB globally. Diagnosis…
Spatial Analysis of Childhood Tuberculosis and Social Determinants in Bandar Lampung
TLDR
The results showed that childhood TB tend to group in middle to high population density and middle proportion of poor families areas, and TB control programs should elaborate social determinant actions in areas with low social determinants.

References

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TLDR
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BACKGROUND Tuberculosis is a large source of morbidity and mortality among children. However, limited studies characterize childhood tuberculosis disease, and contact investigation is rarely…
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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