Prospective assessment of two-stage testing for Clostridium difficile.

  title={Prospective assessment of two-stage testing for Clostridium difficile.},
  author={Amber Arnold and Curran Pope and Sarah C Bray and Peter Riley and Aodh{\'a}n Breathnach and Sanjeev Krishna and T. Planche},
  journal={The Journal of hospital infection},
  volume={76 1},
Commonly used immunoassays have limitations as stand-alone tests for the diagnosis of Clostridium difficile infection (CDI). In particular, the specificity of these assays means that these tests generate a relatively large number of false-positive results. We introduced a two-stage regimen for CDI as routine. Unformed stool samples received in our laboratory were initially tested with a Meridian Premier enzyme immunoassay (EIA) and positive samples were retested with reference testing methods… CONTINUE READING
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