Prospective assessment of XPD Lys751Gln and XRCC1 Arg399Gln single nucleotide polymorphisms in lung cancer.

Abstract

PURPOSE XRCC1 and XPD play key roles in the repair of DNA lesions and adducts. Contrasting findings have been reported on the effect of polymorphisms of these genes on the response to platinum-based chemotherapy in advanced non-small-cell lung cancer (NSCLC). This study aimed to investigate the relationship between the XPD Lys751Gln and XRCC1 Arg399Gln… (More)

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@article{Giachino2007ProspectiveAO, title={Prospective assessment of XPD Lys751Gln and XRCC1 Arg399Gln single nucleotide polymorphisms in lung cancer.}, author={Daniela Francesca Giachino and Paolo Ghio and Silvia Regazzoni and Giorgia Mandrile and Silvia Novello and Giovanni Selvaggi and Dario Gregori and M Demarchi and Giorgio Scagliotti}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2007}, volume={13 10}, pages={2876-81} }