Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C.

@article{Poynard2004ProspectiveAO,
  title={Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C.},
  author={Thierry Poynard and M. J. Munteanu and Françoise Imbert-Bismut and Fr{\'e}d{\'e}ric Charlotte and Dominique Thabut and Sophie Le Calvez and Djamila Messous and Vincent Thibault and Yves Benhamou and Joseph Moussalli and Vlad Ratziu},
  journal={Clinical chemistry},
  year={2004},
  volume={50 8},
  pages={1344-55}
}
BACKGROUND The FibroTest and ActiTest are noninvasive biochemical markers of liver injury that are intended for use as alternatives to liver biopsy in patients with chronic hepatitis C. The aims of this study were to assess the quality of biopsy and the prevalence of discordances between biopsy and markers, to identify factors associated with discordances, and to attribute these discordances to either markers or biopsy failure. METHODS Fibrosis stage and activity grade were prospectively… CONTINUE READING