Prospective Open-Label Clinical Trial of Trihexyphenidyl in Children With Secondary Dystonia due to Cerebral Palsy

@article{Sanger2007ProspectiveOC,
  title={Prospective Open-Label Clinical Trial of Trihexyphenidyl in Children With Secondary Dystonia due to Cerebral Palsy},
  author={Terence D. Sanger and Amy J. Bastian and Janice E. Brunstrom and Diane L. Damiano and Mauricio R Delgado and Leon Dure and Deborah J. Gaebler-Spira and Alexander Hoon and Jonathan W. Mink and Sara Sherman-Levine and Leah J. Welty},
  journal={Journal of Child Neurology},
  year={2007},
  volume={22},
  pages={530 - 537}
}
Although trihexyphenidyl is used clinically to treat both primary and secondary dystonia in children, limited evidence exists to support its effectiveness, particularly in dystonia secondary to disorders such as cerebral palsy. A prospective, open-label, multicenter pilot trial of high-dose trihexyphenidyl was conducted in 23 children aged 4 to 15 years with cerebral palsy judged to have secondary dystonia impairing function in the dominant upper extremity. All children were given… 

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