Prospective Case-Control Study to Evaluate the Role of Glutathione S Transferases (GSTT1 and GSTM1) Gene Deletion in Breast Carcinoma and Its Prognostic Significance.

@article{Bansal2015ProspectiveCS,
  title={Prospective Case-Control Study to Evaluate the Role of Glutathione S Transferases (GSTT1 and GSTM1) Gene Deletion in Breast Carcinoma and Its Prognostic Significance.},
  author={Virinder Kumar Bansal and Karthik Rajan and Arundhati Sharma and Preeti Paliwal and Gaurav Nitin Chaubal and Vikas Jindal and Mahesh Chandra Misra and Kiran Kucheria},
  journal={The Indian journal of surgery},
  year={2015},
  volume={77 Suppl 3},
  pages={1067-72}
}
Breast cancer is the most common cause of cancer death in women with the incidence rising in young women. GST gene polymorphisms are significant because of their role in the detoxification of both environmental carcinogens and also cytotoxic drugs used in therapy for breast cancer. The present study has been designed to identify the role of polymorphisms in GSTT1 and GSTM1 genes in the risk of development of breast cancer, in the prognostication of breast cancer, and in the prediction of… CONTINUE READING
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