Prospective Associations of Vitamin D With β-Cell Function and Glycemia

@inproceedings{Kayaniyil2011ProspectiveAO,
  title={Prospective Associations of Vitamin D With β-Cell Function and Glycemia},
  author={Sheena Kayaniyil and Ravi Retnakaran and Stewart B Harris and Reinhold Vieth and J. A. G. Knight and Hertzel C. Gerstein and Bruce A Perkins and Bernard Zinman and Anthony J. G. Hanley},
  booktitle={Diabetes},
  year={2011}
}
OBJECTIVE To examine the prospective associations of baseline vitamin D [25-hydroxyvitamin D; 25(OH)D] with insulin resistance (IR), β-cell function, and glucose homeostasis in subjects at risk for type 2 diabetes. RESEARCH DESIGN AND METHODS We followed 489 subjects, aged 50 ± 10 years, for 3 years. At baseline and follow-up, 75-g oral glucose tolerance tests (OGTTs) were administered. IR was measured using the Matsuda index (IS(OGTT)) and the homeostasis model assessment of IR (HOMA-IR… CONTINUE READING
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