Propylthiouracil-associated rapidly progressive crescentic glomerulonephritis with double positive anti-glomerular basement membrane and antineutrophil cytoplasmic antibody: the first case report.

@article{Kantachuvesiri2015PropylthiouracilassociatedR,
  title={Propylthiouracil-associated rapidly progressive crescentic glomerulonephritis with double positive anti-glomerular basement membrane and antineutrophil cytoplasmic antibody: the first case report.},
  author={Pitchaporn Kantachuvesiri and Panas Chalermsanyakorn and Bunyong Phakdeekitcharoen and Thitima Lothuvachai and Kannika Niticharoenpong and Piyanuch Radinahamed and Neil Turner and Surasak Kantachuvesiri},
  journal={CEN case reports},
  year={2015},
  volume={4 2},
  pages={
          180-184
        }
}
We report a case of propylthiouracil (PTU)-induced double antineutrophil cytoplasmic antibody (ANCA) and anti-glomerular basement membrane antibody (anti-GBM antibody) disease causing pulmonary-renal syndrome in a 35-year-old Thai woman with 10-year history of PTU treatment for thyrotoxicosis. She developed clinical symptoms of vasculitis upon receiving long-term PTU treatment. Prednisolone treatment and the switching from PTU to methimazole resulted to short-term clinical improvement… CONTINUE READING