Propranolol suppresses reactivation of herpesvirus.

  title={Propranolol suppresses reactivation of herpesvirus.},
  author={Bryan M. Gebhardt and Herbert E. Kaufman},
  journal={Antiviral research},
  volume={27 3},
Herpes simplex virus type 1 (HSV-1) reactivates from the nervous system and causes recurrent disease in end organs such as the eye and the lips. We found that the beta-adrenergic receptor blocker, propranolol, reduces HSV-1 reactivation in an animal model. Mice latent for McKrae strain HSV-1 were injected with propranolol or saline once a day for 3 successive days, and subjected to a brief period of hyperthermia on the second day to induce reactivation. Twenty-four hours after the third… CONTINUE READING