Propranolol reduces rat dopamine-beta-hydroxylase activity and catecholamine levels.

Abstract

Propranolol treatment (1 mg/kg i.p. twice daily for 8 days) reduced atrial dopamine-beta-hydroxylase (D beta H) activity by 60.5% and lung D beta H activity by 53.5% but did not alter ventricle D beta H activity. Propranolol also significantly reduced atrial noradrenaline (NA) by 66.3%, adrenaline (A) by 40%, dopamine (DA) by 72.4% and lung NA by 46.6% but… (More)

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@article{Elayan1992PropranololRR, title={Propranolol reduces rat dopamine-beta-hydroxylase activity and catecholamine levels.}, author={Hadeel Elayan and Brian Kennedy and Moritz Ziegler}, journal={European journal of pharmacology}, year={1992}, volume={212 2-3}, pages={259-62} }