Proposed mechanism for the initiation of transposable element silencing by the RDR6-directed DNA methylation pathway

Abstract

The activity of transposable elements is epigenetically suppressed by both transcriptional and post-transcriptional mechanisms. We recently identified a direct connection between the small RNA-mediated post-transcriptional mRNA degradation of actively transcribing transposable elements and the de novo methylation of transposable element DNA, providing a… (More)
DOI: 10.4161/psb.25206

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