Proposed mechanism for sperm chromatin condensation/decondensation in the male rat

@article{Chapman2003ProposedMF,
  title={Proposed mechanism for sperm chromatin condensation/decondensation in the male rat},
  author={John Christopher Chapman and Sandra D. Michael},
  journal={Reproductive biology and endocrinology : RB&E},
  year={2003},
  volume={1},
  pages={20 - 20}
}
Condensation of sperm chromatin occurs after spermatozoa have left the caput epididymis and are in transit to the cauda epididymis, during which time large numbers of disulfide bonds are formed. The formation of these disulfide bonds requires the repeated oxidation of the cofactor, NAD(P)H. To date, the means by which this oxidation is achieved has yet to be elucidated. Spermatozoa lose the bulk of their cytoplasm prior to leaving the testis; and, as a result, any shuttle systems for removing… CONTINUE READING

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