Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative Group

  title={Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative Group},
  author={John M. Bennett and Daniel Catovsky and Marie‐Theregse Daniel and Georges Flandrin and D. A. G. Galton and H. R. Gralnick and Claude Sultan},
  journal={British Journal of Haematology},
A uniform system of classification and nomenclature of the acute leukaemias, at present lacking, should permit more accurate recording of the distribution of cases entered into clinical trials, and could provide a reference standard when newly developed cell-surface markers believed to characterize specific cell types are applied to cases of acute leukaemia. [] Key Method Proposals based on conventional morphological and cytochemical methods are offered following the study of peripheral blood and bone-marrow…

Classification of acute leukaemias.


It seems, therefore, that L2 may not only be a distinct variant within the ‘lymphoid’ group, but also one with a poorer outlook to successful treatment, and the survival data even in the L1 group are inferior to the results reported by some of the best centres for leukaemia therapy.

Evolution of the French-American-British (FAB) proposals. Is there a place for acute basophilic leukemia?

  • F. Dick
  • Medicine
    American journal of clinical pathology
  • 1991
In 1976 when the French-American-British (FAB) proposals were first published, categorization of acute leukemia seemed simple. This disease was diagnosed and subclassified based primarily on Wright's


  • J. Godyn
  • Medicine
    British journal of haematology
  • 1988
The FAB classification system proposed in 1981 and the CCSG system of using FAB criteria are two different classification systems of ALL and their results are not compatible.

Lineage specific classification of leukaemia: results of the analysis of sixty cases of childhood leukaemia

Summary. In addition to conventional morphological, histochemical and immunological marker studies, cells from 60 children with leukaemia were further analysed using the Southern blot hybridization

Classification of Acute Leukemias Perspective 2

A useful classification of acute leukemia must be reproducible, must impart understanding of leukemogenesis and clinical behavior, and (most importantly) be clinically relevant, which makes such a

importance . leukaemia and its clinical childhood lymphoblastic morphological classification of French American British ( FAB )

The findings confirm earlier reports that FAB L2 ALL is associated with a poor prognosis and that it occurs more commonly in older children and indicates that alternative early treatment may be appropriate for such patients.


Classification of the Acute Leukaemias

A working numerical notation has been devised for the cytomorphological classification of 238 cases of acute leukaemia in adults (20 years and above) admitted by the referring centres in the United