Proportion of blasts with a clear halo around nucleoli at the end of induction therapy of acute myeloid leukemia correlates with achievement of complete remission, remission duration and relapse.

@article{Emura1998ProportionOB,
  title={Proportion of blasts with a clear halo around nucleoli at the end of induction therapy of acute myeloid leukemia correlates with achievement of complete remission, remission duration and relapse.},
  author={Iwao Emura and T Chou and Toru Ishiguro and Toshio Kakihara and Makoto Naito and Hirohisa Yoshizawa and Maki Arakawa},
  journal={Pathology international},
  year={1998},
  volume={48 7},
  pages={526-35}
}
Bone marrow aspirates from 60 patients with acute myeloid leukemia (AML) were investigated using 95% ethanol fixation Papanicolaou stained preparations. The blasts were grouped into those with a clear halo around nucleoli (BCHN) and those without a clear halo. The patients were classified into three groups according to the degree of persistent BCHN at the… CONTINUE READING