Propolis derivatives inhibit the systemic inflammatory response and protect hepatic and neuronal cells in acute septic shock.

@article{Korish2011PropolisDI,
  title={Propolis derivatives inhibit the systemic inflammatory response and protect hepatic and neuronal cells in acute septic shock.},
  author={Aida Abdelhamid Korish and Maha Arafa},
  journal={The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases},
  year={2011},
  volume={15 4},
  pages={332-8}
}
BACKGROUND Severe pathogenic infection triggers excessive release of cytokines as part of the massive inflammatory response associated with septic shock. OBJECTIVES To investigate the protective effect of caffeic acid phenethyl ester (CAPE) against lipopolysaccharide (LPS) induced endotoxemia, hepatic and neuronal damage and the associated systemic inflammatory response (SIR). METHODS Fifty male Wister rats were divided into: control, LPS, and CAPE+LPS groups. Plasma concentrations of… CONTINUE READING

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