Propofol pharmacokinetics in young healthy Indian subjects

  title={Propofol pharmacokinetics in young healthy Indian subjects},
  author={Avinash Puri and Bikash Medhi and Nidhi Bidyut Panda and G. D. Puri and Sanju Dhawan},
  booktitle={Indian journal of pharmacology},
OBJECTIVES To analyze population pharmacokinetics of Propofol in Indian patients after single bolus dose of Propofol using WINNONLIN program. MATERIALS AND METHODS Population pharmacokinetics of Propofol was investigated in Indian subjects in 26 elective surgical patients (14 males and 12 females) following single bolus dose of 2 mg/kg propofol. A total of 364 samples were estimated by High Performance Liquid Chromatography and pharmacokinetic parameters were derived using WINNONLIN (5.2… CONTINUE READING