Propofol infusion syndrome--report of an adult fatality.

  title={Propofol infusion syndrome--report of an adult fatality.},
  author={David Ernest and Craig French},
  journal={Anaesthesia and intensive care},
  volume={31 3},
This report describes a fatal case of the propofol infusion syndrome in an adult patient being sedated for a closed head injury using high doses of propofol. The features of circulatory collapse, metabolic acidosis, mild rhabdomyolysis and renal impairment are consistent with the syndrome and not readily attributable to alternative aetiologies. Potential mechanisms for the syndrome may relate to antagonism of beta-receptors, impaired myocardial oxygen utilization and a specific disruption to… CONTINUE READING
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