Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cells.

Abstract

Propofol is one of the most widely clinically used intravenous anesthetic, and it induces apoptosis in human and murine leukemia cell lines. Yet, whether propofol causes DNA damage and affects the mRNA expression of repair-associated genes in cancer cells remains undetermined. In the present study, we investigated the effects of propofol on DNA damage and… (More)
DOI: 10.3892/or.2013.2722

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