Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium.

@article{Grundmanova2016PropofolinducedMA,
  title={Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium.},
  author={Martina Grundmanova and Dagmar Jarkovska and Anke Suess and Zdenek Tuma and Mark{\'e}ta Markov{\'a} and Z Grundman and Aly I. El-Kadi and Miroslava Cedikova and Milan {\vS}tengl and Jitka Kuncov{\'a}},
  journal={Physiological research},
  year={2016},
  volume={65 Supplementum 5},
  pages={S601-S609}
}
Propofol is a short-acting hypnotic agent used in human medicine for sedation and general anesthesia. Its administration can be associated with serious cardiovascular side-effects that include decrease in arterial blood pressure and cardiac output. The aim of the present study was to evaluate propofol effects on mitochondrial respiration, myocardial… CONTINUE READING