Propofol exerts anti-inflammatory effects in rats with lipopolysaccharide-induced acute lung injury by inhibition of CD14 and TLR4 expression

@inproceedings{Ma2013PropofolEA,
  title={Propofol exerts anti-inflammatory effects in rats with
lipopolysaccharide-induced acute lung injury by inhibition of CD14 and TLR4
expression},
  author={Ling Ma and Xiu-ying Wu and Lihong Zhang and Weimin Chen and Akinori Uchiyama and Takashi Mashimo and Yuji Fujino},
  booktitle={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2013}
}
We investigated the effect of propofol (Prop) administration (10 mg kg-1 h-1, intravenously) on lipopolysaccharide (LPS)-induced acute lung injury and its effect on cluster of differentiation (CD) 14 and Toll-like receptor (TLR) 4 expression in lung tissue of anesthetized, ventilated rats. Twenty-four male Wistar rats were randomly divided into three groups… CONTINUE READING