Propofol attenuates oxidative stress-induced PC12 cell injury via p38 MAP kinase dependent pathway

Abstract

AbstractAim:To investigate the neuroprotective effect of propofol and its intracellular mechanism on neurons in vitro.Methods:Cell viability was determined with 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide reduction. Apoptotic cell death was determined by Hoechst 33258 staining and a fluorescence-activated cell sorter. The caspase-3 activity… (More)
DOI: 10.1111/j.1745-7254.2007.00610.x

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