Propofol and thiopental do not interfere with regional cerebral blood flow response at sedative concentrations.

@article{Veselis2005PropofolAT,
  title={Propofol and thiopental do not interfere with regional cerebral blood flow response at sedative concentrations.},
  author={Robert A. Veselis and Vladimir A. Feshchenko and Ruth A. Reinsel and Bradley Beattie and Timothy J. Akhurst},
  journal={Anesthesiology},
  year={2005},
  volume={102 1},
  pages={26-34}
}
BACKGROUND Anesthetics may affect the regional cerebral blood flow (rCBF) response associated with increased brain activity in humans. rCBF was measured as auditory stimulus rate was increased during propofol and thiopental administration. METHODS After informed consent, 10 right-handed male volunteer participants (aged 33.5 +/- 10.4 yr, weighing 74.5 +/- 8.4 kg) received thiopental (n = 4) or propofol (n = 6) intravenously at stepwise target concentrations of propofol 1.2 and 2.5-3, or… CONTINUE READING

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