Propofol and intralipid interact with reactive oxygen species: a chemiluminescence study.

@article{Demiryrek1998PropofolAI,
  title={Propofol and intralipid interact with reactive oxygen species: a chemiluminescence study.},
  author={Abdullah Tuncay Demiry{\"u}rek and Ismail Cinel and S. Kahraman and M{\"u}ge Tecder-Unal and Nermin G{\"o}ḡ{\"u}ş and Ulku Aypar and Ilker Kanzik},
  journal={British journal of anaesthesia},
  year={1998},
  volume={80 5},
  pages={
          649-54
        }
}
We have studied the ability of propofol and Intralipid to inhibit reactive oxygen species generated either by stimulated human leucocytes or cell-free systems using luminol chemiluminescence. Human leucocytes were stimulated by a chemotactic peptide, FMLP 1 mumol litre-1, or by a phorbol ester, PMA (protein kinase C activator) 0.1 mumol litre-1. In cell-free experiments, superoxide-hydrogen peroxide, hypochlorous acid or hydroxyl radical-induced chemiluminescence responses were initiated by… Expand
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