Propofol and Aminophylline Antagonize Each Other During the Mobilization of Intracellular Calcium in Human Umbilical Vein Endothelial Cells

  title={Propofol and Aminophylline Antagonize Each Other During the Mobilization of Intracellular Calcium in Human Umbilical Vein Endothelial Cells},
  author={Hee Jeong Son and Young-Cheol Lim and Kwon-Soo Ha and Seongsik Kang and Il Young Cheong and Sang-Jin Lee and Seung-Woo Park and Byeong Moon Hwang},
  journal={Journal of Korean Medical Science},
  pages={1222 - 1227}
This study examined whether propofol and aminophylline affect the mobilization of intracellular calcium in human umbilical vein endothelial cells. Intracellular calcium was measured using laser scanning confocal microscopy. Cultured and serum-starved cells on round coverslips were incubated with propofol or aminophylline for 30 min, and then stimulated with lysophosphatidic acid, propofol and aminophylline. The results were expressed as relative fluorescence intensity and fold stimulation… 

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