Propofol: an anesthetic possessing neuroprotective effects.

  title={Propofol: an anesthetic possessing neuroprotective effects.},
  author={Wei-feng Fan and X Zhu and Long-Jun Wu and Z Wu and D Li and F Huang and H-w He},
  journal={European review for medical and pharmacological sciences},
  volume={19 8},
Propofol is a short-acting intravenous anaesthetic agent and widely used not only in operating rooms but also in the intensive care unit (ICU). Apart from its multiple anaesthetic advantages, the neuroprotective effect of propofol has been demonstrated in diverse models of neuronal injury. The effect of propofol results from activation of gamma-aminobutyric acid (GABA) receptor, modulation excitatory amino acid transmitter system and protecting brain cells against oxidative stress. Moreover… CONTINUE READING


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