Propofol: A New Intravenous Anesthetic

  title={Propofol: A New Intravenous Anesthetic},
  author={Peter s. Sebel and Jane D. Lowdon},
Assessing Propofol Induction of Anesthesia Dose Using Bispectral Index Analysis
The dose of propofol assessed by BIS analysis results in an important reduction of prop ofol requirement without side effects.
Prolonged spontaneous movement following emergence from propofol/nitrous oxide anesthesia.
A patient who, despite an intact mental status, experienced new onset of involuntary myoclonic-dystonic motor movement which lasted several days following emergence from a propofol/nitrous oxide anesthetic is presented.
Propofol inhibits stromatoxin-1-sensitive voltage-dependent K[sup]+[sup] channels in pancreatic β-cells and enhances insulin secretion
The effects of the intravenous anesthetic propofol on glucose metabolism and insulin sensitivity are largely unknown at present.
Induction Agents for Endotracheal Intubation in Severe Sepsis and Septic Shock
The management of severe sepsis and septic shock remains to this day one of the great challenges in medical care and cross the threshold of multiple medical disciplines.
Assessment of propofol anesthesia in the rabbit
Sedation and Analgesia for Diagnostic and Therapeutic Procedures
Practice Guidelines for Pediatric Sedation, Nursing Perspectives on the Care of Sedated Patients, and Quality Assurance and Continuous Quality Improvement in Sedation Analgesia.
Propofol in patients with cardiac disease
  • N. Searle, P. Sahab
  • Medicine
    Canadian journal of anaesthesia = Journal canadien d'anesthesie
  • 1993
Compared with other iv anaesthetics, the induction dose of propofol has a relatively higher incidence of respiratory depression, short-lived apnoea and blood pressure reduction that may occasionally be marked.
Comparison of the effects of patient controlled analgesia (PCA) using dexmedetomidine and propofol during septoplasty operations: a randomized clinical trial
Dexmedetomidine can be used safely as an analgesic and sedation drug in septoplastic surgery, and patient satisfaction via patient-controlled anesthesia and analgesic demand was high.
Propofol Suppresses Macrophage Functions and Modulates Mitochondrial Membrane Potential and Cellular Adenosine Triphosphate Synthesis
A clinically relevant concentration of propofol can suppress macrophage functions, possibly through inhibiting their mitochondrial membrane potential and adenosine triphosphate synthesis instead of direct cellular toxicity.
“The Induction Dose with Ketamine and Midazolam Co-Induction to Propofola”
This study showed that hemodynamic variables were maintained within the physiological range with midazolam and ketamine co-induction, however, lesser degree of decrease in mean arterial pressure was seen with ketamine but the heart rate was higher.