Propofol, but not etomidate, reduces desflurane-mediated sympathetic activation in humans.


PURPOSE The administration of desflurane to humans can lead to substantial activation of the neurohumoral axis. Propofol can inhibit the sympathetic response to stress. This study compared the neurocirculatory effects of induction of anesthesia with propofol with those of etomidate on desflurane-mediated sympathetic activation. METHODS After informed… (More)