Propionibacterium acnes induces IL-1β secretion via the NLRP3 inflammasome in human monocytes

Abstract

Propionibacterium acnes induction of inflammatory responses is a major etiological factor contributing to the pathogenesis of acne vulgaris. In particular, the IL-1 family of cytokines has a critical role in both initiation of acne lesions and in the inflammatory response in acne. In this study, we demonstrated that human monocytes respond to P. acnes and… (More)
DOI: 10.1038/jid.2013.309

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