Propionibacterium acnes: infection beyond the skin

@article{Perry2011PropionibacteriumAI,
  title={Propionibacterium acnes: infection beyond the skin},
  author={A. Perry and P. Lambert},
  journal={Expert Review of Anti-infective Therapy},
  year={2011},
  volume={9},
  pages={1149 - 1156}
}
  • A. Perry, P. Lambert
  • Published 2011
  • Biology, Medicine
  • Expert Review of Anti-infective Therapy
Propionibacterium acnes is a Gram-positive bacterium that forms part of the normal flora of the skin, oral cavity, large intestine, the conjunctiva and the external ear canal. Although primarily recognized for its role in acne, P. acnes is an opportunistic pathogen, causing a range of postoperative and device-related infections. These include infections of the bones and joints, mouth, eye and brain. Device-related infections include those of joint prostheses, shunts and prosthetic heart valves… Expand
Propionibacterium acnes in Human Health and Disease
TLDR
This special issue aims to provide a description of recent developments and advances in different areas of P. acnes research via original research and review articles, and provide a framework to discuss and identify key issues that need to be addressed in future studies. Expand
The role of Propionibacterium acnes in and Modic type 1 changes : A literature review.
TLDR
Identification of P. acnes in culture indicates the infective patho-mechanism in the pathogenesis of Modic type 1 changes, which may be ameable to antibiotic treatment, but it is still difficult to identify which subset of these patients (patients with low back pain with type 1 Modic change) are infective in nature. Expand
Management of Propionibacterium acnes infection after shoulder surgery
TLDR
Penicillin and cephalosporins are effective against clinical P. acnes infection and biofilm in vitro, and combination antibiotic therapy with rifampin and daptomycin may further increase the clinical efficacy of treatment. Expand
Propionibacterium acnes: An Underestimated Pathogen in Implant-Associated Infections
TLDR
The pathogenic role of P. acnes in implant-associated infections such as prosthetic joints, cardiac devices, breast implants, intraocular lenses, neurosurgical devices, and spine implants is reviewed and sonication of explanted prosthetic material improves the diagnosis of implant- associated infections. Expand
Cutibacterium (formerly Propionibacterium) acnes infections associated with implantable devices
TLDR
Cutibacterium acnes, a Gram-positive biofilm-forming rod implicated in acne vulgaris, is increasingly recognized for its role in implant-associated infections and research should focus on developing effective anti-biofilm agents. Expand
PROPIONIBACTERIUM ACNES AND THE SKIN DISEASE OF ACNE VULGARIS. PROPIONIBACTERIUM ACNES ȘI IMPLICAREA LUI ÎN ACNEEA VULGARĂ
TLDR
This review has a look on different characteristics of P.acnes and the related skin disease of acne vulgaris. Expand
Cutibacterium acnes is an intracellular and intra-articular commensal of the human shoulder joint.
TLDR
Data indicate that C acnes is a commensal of the human shoulder joint, where it persists within macrophages and stromal cells, and may link its intra-articular presence to the initiation of osteoarthritis. Expand
Propionibacterium acnes and bacterial resistance
TLDR
The present article is aimed at updating dermatologists with the most current data – from the classification to the physiopathogenic mechanisms involved in bacterial resistance to P. acnes and its possible clinical implications. Expand
Clinical Features of Infectious Keratitis Caused by Propionibacterium Acnes
TLDR
Propionibacterium acnes is a commensal bacteria whose pathogenicity in infectious keratitis is unclear and can be confused with other Gram-positive cocci, so P. acnes should be suspected in small-sized ker atitis with an unusually long incubation period. Expand
First case of Propionibacterium acnes urinary tract infection in a dog
TLDR
This is the first case report of a dog with urinary tract infection caused by P. acnes and this isolate showed high susceptibility to ampicillin, amoxicillin/clavulanic acid, cefoxitin, imipenem, clindamycin, tetracycline, chloramphenicol, and enrofloxacin, but was resistant to metronidazole. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 110 REFERENCES
[Propionibacterium acnes infective endocarditis. Study of 11 cases and review of literature].
TLDR
P. acnes can be the cause of IE long before it has been detected, and requires a thorough knowledge of the clinical context before concluding to contamination, and mandates close surveillance of the patient. Expand
Propionibacterium acnes: an agent of prosthetic joint infection and colonization.
TLDR
Findings suggest infection in most of the patients whose PJI symptoms appeared: < or = 2 years after the index operation, and colonization in the majority of those whose symptoms appeared >2 years after index surgery. Expand
Propionibacterium acnes as an etiological agent of arthroplastic and osteosynthetic infections--two cases with specific clinical presentation including formation of draining fistulae.
TLDR
Potypic and genetic characterisation of the isolates clearly emphasizes the significance of P. acnes as an etiological agent of implant infections, which are insidious with delayed presentation of symptoms and may have been overlooked because of the frequent use of suboptimal culture procedures. Expand
Indigenous pulmonary Propionibacterium acnes primes the host in the development of sarcoid-like pulmonary granulomatosis in mice.
TLDR
This is the first report to present clear evidence of the contribution of an indigenous pulmonary bacterium to the formation of granulomatous lesions in the lung, and it is proposed that treatment targeting indigenous P. acnes in the lungs may be a possible remedy for pulmonary sarcoidosis. Expand
Isolation of Propionibacterium acnes from central nervous system infections.
TLDR
Propionibacterium acnes is a common skin colonizer and its involvement in central nervous system (CNS) infections may be related with previous neurosurgical procedures and infections must be surgically managed under adequate antibiotic treatment. Expand
"SAPHO syndrome and infections".
TLDR
The current concept of SAPHO syndrome as a reactive infectious osteitis in genetic predisposed subjects seems appealing, but it has not been yet demonstrated. Expand
Biofilm formation by Propionibacterium acnes is a characteristic of invasive isolates.
  • A. Holmberg, R. Lood, +5 authors M. Rasmussen
  • Biology, Medicine
  • Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2009
TLDR
The presence of human plasma in solution or at the plastic surface inhibits biofilm formation, which could explain why P. acnes primarily infect plasma-poor environments of, for example, joint prostheses and cerebrospinal shunts. Expand
The Prevalence and Pathogenicity of Propionibacterium acnes Keratitis
TLDR
Evidence is provided that P. acnes is a frequent cause of bacterial keratitis and may cause significant morbidity and the most common risk factors were contact lens wear and previous history of ocular surgery. Expand
The Complete Genome Sequence of Propionibacterium Acnes, a Commensal of Human Skin
TLDR
The entire genome sequence of this Gram-positive bacterium encodes 2333 putative genes and revealed numerous gene products involved in degrading host molecules, including sialidase, neuraminidases, endoglycoceramidased, lipases, and pore-forming factors. Expand
Complete Genome Sequence of Propionibacterium acnesType IB Strain 6609
TLDR
The whole genome sequence of P. acnes type IB strain 6609 is presented, which was recovered from a skin sample from a woman with no recorded acne history and is thus considered a nonpathogenic strain. Expand
...
1
2
3
4
5
...