Prophylaxis of upper gastrointestinal bleeding with cimetidine in patients undergoing partial hepatectomy.


The aim of this study was to evaluate the effect of cimetidine on prophylaxis of upper gastrointestinal (GI) bleeding from acute mucosal lesions or stress ulcers of the stomach and duodenum after partial hepatectomy. Five (27.8%) of 18 control patients had upper GI bleeding v.s. only two (5.9%) of 34 cimetidine treated patients (P less than 0.05). The… (More)